CBD research on - Neurodegeneration
2017: Cannabidiol reduces neuroinflammation and promotes neuroplasticity and functional recovery after brain ischemia
Collectively, the present results demonstrate that short-term CBD treatment results in global functional recovery in ischemic mice and impacts multiple and distinct targets involved in the pathophysiology of brain ischemic injury.
2017: Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?
CBD acts not only through the endocannabinoid system, but also causes direct or indirect activation of metabotropic receptors for serotonin or adenosine, and can target nuclear receptors of the PPAR family and also ion channels.